Page 42 - SaxoCell Annual Report22/23
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Why macrophages?
Tumor encapsulates Macrophages invade ...but are reprogrammed Tumor continues
itself tumor... by the tumor to grow
DKO macrophages can no longer be reprogrammed
Macrophages in which transcription factors involved in the self-renewal process have been knocked out (double knockout
macrophages, DKO macrophages) can no longer be reprogrammed by the tumor environment.
At the Science4Life Venture Cup - the most important business plan competition for the life
sciences in Germany - we came fourth in the business plan phase (out of 87 participating teams),
beating strong competition! This is an important boost for our ambitions to found a company
based on self-renewing human macrophages.
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